Chraïbi M, Harmouch T, Znati K, El Fatemi H, Chbani L, Bennis S, Amarti A, Ahallal Y, Farih My H
Service d'anatomie et cytologie pathologique, CHU Hassan II, Fès, Maroc.
Prog Urol. 2012 Jan;22(1):70-2. doi: 10.1016/j.purol.2011.02.014. Epub 2011 Apr 20.
Buschke-Lowenstein tumour (BLT) is a giant condyloma acumina, which is rare entity and represents only 1% of all populace. It is a rare viral disease, essentially transmitted by sexual intercourse, characterized by a potential for malignant transformation, invasion and recurrence after treatment. We report a case of BLT associated with perinea-scrotal melanoma. This association was never described in the literature. The purpose of our case report is to discuss the clinical and pathological appearances of these two entities and to outline the recent studies of molecular biology, which can explain this association.
Buschke-Lowenstein肿瘤（BLT）是一种巨大尖锐湿疣，是一种罕见的疾病，仅占所有病例的1%。它是一种罕见的病毒性疾病，主要通过性交传播，其特点是有恶变、侵袭及治疗后复发的可能性。我们报告1例与会阴-阴囊黑色素瘤相关的BLT病例。这种关联在文献中从未被描述过。我们病例报告的目的是讨论这两种疾病的临床和病理表现，并概述最近的分子生物学研究，这些研究可以解释这种关联。
