Guiguemdé R T, Gbary R A, Coulibaly S O, Ouedraogo J B
Organisation de coordination et de coopération pour la lutte contre les Grandes Endémies/Centre Muraz, Centre de référence de la chimiorésistance du paludisme (CRCP), Burkina Faso.
Sante. 1996 May-Jun;6(3):187-91.
Since the emergence of chemoresistant malaria in Africa at the end of the 1970's, many scientific papers have been published. However, terms used in chemoresistant studies and interpretation of tests are not always appropriate. Based on the usual operative definitions, this paper updates methods of chemoresistance study, interpretation of tests and the course of action to take in case of resistance. Our emphasis is on symptomatic people. We distinguish the clinical response and the parasitological response, two notions which are often confused. A diagram is presented for interpreting the different types of responses of in vivo testing in symptomatic people. For adequate case management of malaria, rigorous analysis of chemoresistant malaria and accurate interpretation of the test results are required.
自20世纪70年代末非洲出现抗药性疟疾以来，已发表了许多科学论文。然而，抗药性研究中使用的术语和检测结果的解释并不总是恰当的。基于通常的操作定义，本文更新了抗药性研究方法、检测结果的解释以及出现抗药性时应采取的行动方案。我们重点关注有症状的人群。我们区分了临床反应和寄生虫学反应，这两个概念常常被混淆。本文给出了一个图表，用于解释有症状人群体内检测的不同类型反应。为了对疟疾进行适当的病例管理，需要对抗药性疟疾进行严格分析并准确解释检测结果。
