Initiation of human parturition. VIII. Metabolism of progesterone by fetal membranes of early and late human gestation.
作者信息
Milewich L, Gant N F, Schwarz B E, Chen G T, MacDonald P C
出版信息
Obstet Gynecol. 1977 Jul;50(1):45-8.
PMID:876521
Abstract
A decreased rate of progesterone metabolism is detected in human fetal membranes several weeks preceding normal parturition at term. A 10- to 20-fold decrease in 20alpha-hydroxysteroid oxidoreductase activity and a 2- to 6-fold decrease in 5alpha-reductase activity are observed in human amnion and chorion laeve after 33 weeks' gestation.
摘要
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