Felix K, Ferrándiz R, Einarsson R, Dreborg S
Department of Paediatrics, Faculty of Health Sciences, University of Linköping, Sweden.
J Allergy Clin Immunol. 1996 Jul;98(1):169-71. doi: 10.1016/s0091-6749(96)70239-7.
Some patients who are allergic to horses have reported that they can tolerate certain breeds, and the presence of breed-specific allergens has been suggested. Breeders and patients with asthma have claimed that Bashkir horses are nonallergenic. We used sodium dodecylsulfate-polyacrylamide gel electrophoresis and immunoblotting to determine IgE-binding profiles of extracts of dander obtained from horses of several breeds. We found considerable inter-breed and within-breed variation but no breed-specific allergens. Danders from all breeds investigated contained the most important allergens, and the allergenic content of dander from Bashkir horses was similar to that of other breeds. Difference in scale production could account for differences in sensitivity to breeds and individual horses.
一些对马过敏的患者报告称，他们能够耐受某些品种的马，因此有人提出存在品种特异性过敏原。饲养者和哮喘患者称巴什基尔马不会引起过敏。我们采用十二烷基硫酸钠-聚丙烯酰胺凝胶电泳和免疫印迹法来确定从几个品种的马身上获取的皮屑提取物的IgE结合谱。我们发现品种间和品种内均存在相当大的差异，但没有品种特异性过敏原。所有被调查品种的皮屑都含有最重要的过敏原，巴什基尔马皮屑的过敏原含量与其他品种相似。规模生产的差异可能导致对不同品种和个体马匹的敏感性存在差异。
