Maier W, Marangos N, Aschendorff A
Hals-Nasen-Ohren-Klinik der Albert-Ludwigs-Universität Freiburg.
Laryngorhinootologie. 1996 Jun;75(6):372-6. doi: 10.1055/s-2007-997597.
Lermoyez's syndrome is usually regarded as a rare variant of Menière's disease with hearing improvement and reduction of tinnitus during vertiginous attacks. Electrocochleographic studies of this syndrome are restricted to one published case up to now.
In our ENT department we clinically and electrocochleographically examined three patients suffering from Lermoyez's syndrome. These results were compared to those typically found in Menière patients.
Two of the three patients did not show an elevated summating potential or increased ratio of summating potential and compound action potential (SP/CAP ratio). There was no hearing improvement following oral glycerol administration, and the SP/CAP ratio did not change during a Lermoyez attack. On the other hand, we observed normal cochlear microphonics in ears affected by Lermoyez's syndrome, indicating good hair cell function. In one ear, the threshold of cochlear microphonics was even better than the pure tone threshold.
Our observations suggest that endolymphatic hydrops may not be always the underlying pathologic correlate of Lermoyez's syndrome. Thus Lermoyez's syndrome should not be simply regarded as a variant of Menière's disease.
莱莫耶兹综合征通常被视为梅尼埃病的一种罕见变体，在眩晕发作期间听力改善且耳鸣减轻。截至目前，该综合征的电耳蜗图研究仅限于一篇已发表的病例。
在我们的耳鼻喉科，我们对三名患有莱莫耶兹综合征的患者进行了临床和电耳蜗图检查。将这些结果与梅尼埃病患者的典型结果进行比较。
三名患者中有两名未显示总和电位升高或总和电位与复合动作电位的比率增加（SP/CAP比率）。口服甘油后听力未改善，在莱莫耶兹发作期间SP/CAP比率也未改变。另一方面，我们观察到受莱莫耶兹综合征影响的耳朵中耳蜗微音电位正常，表明毛细胞功能良好。在一只耳朵中，耳蜗微音电位的阈值甚至优于纯音阈值。
我们的观察结果表明，内淋巴积水可能并不总是莱莫耶兹综合征的潜在病理相关因素。因此，莱莫耶兹综合征不应简单地被视为梅尼埃病的一种变体。
