Schoonhoven R, Schmidt P H, Eggermont J J
ENT Department, University Hospital, Leiden, The Netherlands.
Eur Arch Otorhinolaryngol. 1990;247(6):333-9. doi: 10.1007/BF00179001.
An 18-year follow-up of a case of bilateral Lermoyez's syndrome is presented. The left ear having reached a stabilized hearing loss about 9 years after the onset of the disease, the right ear, apart from some isolated early periods of hearing loss, started to show the full extent of clinical symptoms after about 16 years. Electrocochleographic observations are presented. Studies were performed twice in the right ear during a period of strongly fluctuating hearing thresholds, once in an impaired and once in a relatively good condition. Electrocochleography of the stabilized left ear was performed as well. The data are compared with electrocochleographical observations in the left ear in its early fluctuating stage. Variation of cochlear physiological data during the fluctuating stage of the disease shows remarkable correspondence between the two ears. The stabilized Lermoyez ear is shown to have developed considerable hair cell loss, but may still have preserved its endolymphatic hydrops. These findings in Lermoyez's syndrome fit well into the observations reported in patients with Menière's disease.
本文报告了一例双侧Lermoyez综合征患者的18年随访情况。左耳在发病约9年后听力损失趋于稳定，右耳除了在疾病初期有一些孤立的听力损失期外，大约16年后开始出现完整的临床症状。文中呈现了电耳蜗图观察结果。在右耳听力阈值剧烈波动期间进行了两次研究，一次是在听力受损时，一次是在听力相对较好时。同时也对稳定期的左耳进行了电耳蜗图检查。将这些数据与左耳早期波动期的电耳蜗图观察结果进行了比较。疾病波动期耳蜗生理数据的变化表明，双耳之间存在显著的对应关系。稳定期的Lermoyez耳显示出大量毛细胞丢失，但可能仍保留内淋巴积水。Lermoyez综合征的这些发现与梅尼埃病患者的观察结果非常吻合。
