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10岁以下儿童溃疡性结肠炎:内科及外科治疗

Ulcerative colitis in children under 10 years of age: medical and surgical treatment.

作者信息

Rivosecchi M, Lucchetti M C, Dall'Oglio L, Ponticelli A, Federici G, Zaccara A, Ferretti F, Castro M

机构信息

Department of Paediatric Surgery and Gastroenterology Bambino Gesù Children's Hospital Rome, Italy.

出版信息

Acta Chir Belg. 1996 Jun;96(3):104-7.

PMID:8766599
Abstract

Ulcerative colitis is seen with increasing frequency in paediatric age and its diagnosis is made more difficult by atypical cases. Sixty-five patients with UC were seen at our institute and all of them underwent medical treatment. In all patients the disease extended to the whole colon (pancolitis). Eleven patients (average age 9 yrs) underwent surgical correction by Endorectal Pull Through (EPT) 8 straight and 3 with ileal reservoir. One straight EPT had to be converted to Brooke ileostomy because of unacceptable stool frequency. In the rest of the patients the disease is well controlled with medical treatment. After 2 years of follow up surgical complications, continence, stool frequency and quality of life were evaluated: results indicate that surgical complications rate is the same as in other reported series; furthermore, continence and stool frequency are good with all surgical techniques eve though straight pull-through may require a period of adaptation the length of which varies considerably. Our results confirm that children with pancolitis and severe symptoms should be offered prolonged medical treatment prior to undertake surgical correction.

摘要

溃疡性结肠炎在儿童期的发病率日益增加,非典型病例使其诊断更加困难。我院共诊治了65例溃疡性结肠炎患者,所有患者均接受了药物治疗。所有患者的病变均累及全结肠(全结肠炎)。11例患者(平均年龄9岁)接受了经直肠拖出术(EPT)的手术矫正,其中8例为直接拖出术,3例采用回肠贮袋术。1例直接拖出术患者因排便频率无法接受而改行布鲁克回肠造口术。其余患者的病情通过药物治疗得到了良好控制。随访2年后,对手术并发症、控便能力、排便频率和生活质量进行了评估:结果表明,手术并发症发生率与其他报道系列相同;此外,尽管直接拖出术可能需要一段时间的适应期,且适应期长短差异很大,但所有手术技术的控便能力和排便频率均良好。我们的结果证实,患有全结肠炎且症状严重的儿童在进行手术矫正之前应接受长期药物治疗。

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