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[鞘内注射吗啡和布比卡因治疗慢性胰腺炎的重度疼痛]

[Intrathecal administration of morphine and bupivacaine in the treatment of severe pain in chronic pancreatitis].

作者信息

Verheijen R, Slappendel R, Jansen J B, Crul B J, van Dongen R T

机构信息

Pijnteam/Instituut voor Anesthesiologie, Academisch Ziekenhuis, Nijmegen.

出版信息

Ned Tijdschr Geneeskd. 1996 Jul 6;140(27):1410-2.

PMID:8766685
Abstract

A 25-year-old male with idiopathic chronic pancreatitis suffered from severe pain not reacting to medical therapy. Intractable pain persisted after the following procedures: subtotal resection of the pancreas, interpleural administration of bupivacaine, epidural administration of bupivacaine, and thoracoscopic sympathectomy. Eventually, adequate pain relief was achieved with intrathecal administration of morphine and bupivacaine. An infusion pump, externally controlled by radiotelemetry, was implanted subcutaneously for intrathecal drug administration. With this pump the patient was fully ambulant. Intrathecal administration of morphine and bupivacaine through an implanted pump is a possible new technique for pain management in chronic pancreatitis.

摘要

一名25岁的特发性慢性胰腺炎男性患者,遭受严重疼痛,药物治疗无效。在进行了以下手术后,顽固性疼痛仍持续存在:胰腺次全切除术、布比卡因胸膜内给药、布比卡因硬膜外给药和胸腔镜交感神经切除术。最终,鞘内注射吗啡和布比卡因实现了充分的疼痛缓解。通过无线电遥测进行外部控制的输液泵被皮下植入用于鞘内给药。借助这个泵,患者能够完全自主活动。通过植入泵进行鞘内注射吗啡和布比卡因是慢性胰腺炎疼痛管理的一种可能的新技术。

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