Mandigers C M, Mensink E J, Geurts van Kessel A, van der Plas D C, Haanen C, Hagemeÿer A, de Witte T
University Hospital Nijmegen, Department of Hematology, The Netherlands.
Ann Hematol. 1996 Jun;72(6):371-3. doi: 10.1007/s002770050188.
A 44-year-old man suffering from cytogenetically and molecularly proven Philadelphia translocation-positive chronic myelogenous leukemia in chronic phase was treated with busulfan for 18 months and studied during a follow-up period of 13 years. Hematologically and cytogenetically, he attained a continuing complete remission, although at one point (9.5 years) at least, after attaining complete remission molecular analysis indicated the presence of minimal residual disease.
一名44岁男性，经细胞遗传学和分子学证实为费城染色体易位阳性的慢性期慢性粒细胞白血病，接受白消安治疗18个月，并在13年的随访期内进行研究。血液学和细胞遗传学方面，他持续完全缓解，尽管至少在一个时间点（9.5年），在达到完全缓解后分子分析显示存在微小残留病。
