Schultheis K H, Kosicki C, Ruckriegel S, Meyer W, Gebhardt C, Kaiser A, Wünsch P
Klinik für Abdominal-, Thorax- und Endokrine Chirurgie, Städt. Klinikum Nürnberg.
Zentralbl Chir. 1996;121(6):442-9.
Between 1.1.1988 and 31.12.1989 306 patients underwent curative surgery for colorectal cancer at the surgical center of Nurnberg City hospital. The pathohistological findings showed that a carcinomatous lymphangiosis and hemangiosis (LH+) was present in 57 (18.6%) cases. The rate of metachronic metastases of the liver was significantly higher (38.2% vs. 19.6% p < 0.001) compared to patients without lymphangiosis and hemangiosis (LH-). There were also significant differences between the survival rates (5-year survival rate 50% vs. 63% p < 0.02). Analysing the lymph node stage and LH+ situation it was found that carcinomatous lymphangiosis and hemangiosis were already present in 7.2% of patients who didn't have tumorous infiltration of the lymph nodes (p NO/LH+). The 5-year survival rate was bad in both groups (54% vs. 49%).
1988年1月1日至1989年12月31日期间，306例患者在纽伦堡市立医院外科中心接受了结直肠癌根治性手术。病理组织学检查结果显示，57例（18.6%）存在癌性淋巴管及血管浸润（LH+）。与无淋巴管及血管浸润（LH-）的患者相比，肝异时性转移率显著更高（38.2%对19.6%，p<0.001）。生存率之间也存在显著差异（5年生存率50%对63%，p<0.02）。分析淋巴结分期和LH+情况发现，在无淋巴结肿瘤浸润的患者中，7.2%已存在癌性淋巴管及血管浸润（pNO/LH+）。两组的5年生存率均较差（54%对49%）。
