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Quinolone derivatives: synthesis and binding evaluation on cholecystokinin receptors.

作者信息

Varnavas A, Lassiani L, Luxich E, Zacchigna M, Boccù E, Pichierri F

机构信息

Dipartimento di Scienze Farmaceutiche, Università di Trieste, Italy.

出版信息

Farmaco. 1996 May;51(5):341-50.

PMID:8767844
Abstract

A series of 1,2-dihydro-4-phenylquinolin-2-one-3-carboxylic acid and of 3-amino-4-phenylcarbostyril derivatives were synthesized and examined for their CCK receptor affinities. These compounds displayed micromolar affinities for CCK-A rather than CCK-B receptor and the results have been discussed on the basis of a molecular modelling study.

摘要

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