Gilsanz F, Gómez-Tabera C, Torres M, Barredo M, Esténoz J, López-Carbajo A, Millán I
Servicio de Hematología, Hospital Doce de Octubre, Madrid.
Rev Clin Esp. 1996 May;196(5):289-92.
To analyze the usefulness of some reference values for erythropoiesis in the elderly. Methods. A total of 226 individuals older than 65 years (139 females and 87 males) were studied with measurements of hemoglobin (Hb), corpuscular indexes, red blood cell distribution index, serum iron level, ferritin and creatinine. Plasma erythropoietin (EPO) was determined in 72 cases. Values were grouped according to age, younger (126) and older than 76 years (100), and sex.
Hb was lower in males older than 76 years than in individuals younger than 76 years but this differences was not observed among women. Serum iron level was low in 13.3% of individuals. Creatinine was higher among males than among women and higher among males younger than 76 years than in males older than 76 years. EPO was higher among the elderly patients than in young adults (p < 0.001), keeping no relationship with age.
With the exception of EPO, the usual reference values for erythropoiesis in the adults can be used for the elderly patients. Despite differences in EPO compared with adults, the quantitation of this finding is useless for the diagnosis of anemia in the elderly.
分析老年人红细胞生成一些参考值的实用性。方法。对226名65岁以上个体（139名女性和87名男性）进行研究，测量血红蛋白（Hb）、血细胞指数、红细胞分布指数、血清铁水平、铁蛋白和肌酐。对72例患者测定血浆促红细胞生成素（EPO）。根据年龄（较年轻者，126例；76岁以上者，100例）和性别对数值进行分组。
76岁以上男性的Hb低于76岁以下个体，但女性中未观察到这种差异。13.3%的个体血清铁水平较低。男性的肌酐高于女性，76岁以下男性的肌酐高于76岁以上男性。老年患者的EPO高于年轻成年人（p < 0.001），且与年龄无关。
除EPO外，成年人红细胞生成的常用参考值可用于老年患者。尽管与成年人相比EPO存在差异，但该结果的定量对老年贫血的诊断并无用处。
