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[坏死性急性胰腺炎的再次手术:病理生理学评估与外科治疗]

[Reoperation in necrotizing acute pancreatitis: evaluation of physiopathology and surgical treatment].

作者信息

Serio G, Mangiante G, Iacono C, Facci E, Aurola P P

机构信息

Dipartimento di Scienze Chirurgiche, Università degli Studi di Verona.

出版信息

Chir Ital. 1995;47(2):43-9.

PMID:8768086
Abstract

We reviewed our experience of PAN cases operated for complications after a first laparotomy over the period 1992-1994. Over 29 PAN cases, 7 (24%) had been submitted to a second laparotomy or more. Total mortality rate of PAN was 10.3%, while mortality rate of relaparotomy was 14.2%. Haemorrhage and intra-abdominal sepsis were the main cause of relaparotomy (42.8% of the re-operations in both cases). Abdominal wall abscesses (14%) were treated locally; enteric or pancreatic fistulas (34%) were successful treated by drugs, such as somatostatin and octreotide, and / or by total parenteral nutrition. The main diagnostic tools to evaluate clinical course of the patients were computed tomography scan, that seems to gain serial staging of the necrosis and the septic collections. Arteriography is necessary to identify the bleeding source and to perform temporary embolization in the massive arterial haemorrhage before surgical treatment. Moreover, we need radiological exploration to explain fistulas pathways. According to circumstances, we can perform surgically the definitive hemostasis, the pancreatojejunostomy in pancreatic fistulas, and the digestive reconstruction in enteric fistulas. At all events the debridement of necrosis and septic collection is necessary. Up to date, there are not prognostic differences between "closed laparotomy" and "open laparotomy", and we think that the choice is determined only by individual believing of the surgeon.

摘要

我们回顾了1992 - 1994年期间因首次剖腹手术后并发症而接受手术的坏死性胰腺炎(PAN)病例的经验。在29例PAN病例中,7例(24%)接受了二次或更多次剖腹手术。PAN的总死亡率为10.3%,而再次剖腹手术的死亡率为14.2%。出血和腹腔内感染是再次剖腹手术的主要原因(两种情况的再次手术中均占42.8%)。腹壁脓肿(14%)采用局部治疗;肠瘘或胰瘘(34%)通过生长抑素和奥曲肽等药物和/或全胃肠外营养成功治疗。评估患者临床病程的主要诊断工具是计算机断层扫描,它似乎有助于对坏死和感染灶进行连续分期。血管造影对于确定出血源以及在手术治疗前对大量动脉出血进行临时栓塞是必要的。此外,我们需要影像学检查来解释瘘管路径。根据具体情况,我们可以进行确定性止血手术、胰瘘的胰空肠吻合术以及肠瘘的消化重建手术。无论如何,坏死组织和感染灶的清创是必要的。迄今为止,“关闭式剖腹手术”和“开放式剖腹手术”之间没有预后差异,我们认为选择仅由外科医生的个人信念决定。

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