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[不同甲状腺病理患者活检材料中淋巴细胞群体的形态计量学研究]

[A morphometric study of the lymphoid cell population in biopsy material from patients with different thyroid pathologies].

作者信息

Kirillov V A, Iushchenko Iu P, Demidchik E P

出版信息

Tsitologiia. 1996;38(1):89-94.

PMID:8768554
Abstract

Using cytometry of lymphocytes, prolymphocytes and lymphoblasts in touch smears of biopsy and autopsy samples of thyroid, it was revealed that in cancer the small lymphocytes, in the total population of these lymphoid cells, comprise 0-2%, and on distributional histograms of lymphoid cells, according to the average diameter, the maximum was in the range of 9.6-11.7 microns. In benign malformations, goiters and autoimmune thyroiditis, and in the norm the percentage of small lymphocytes varied in the range of 10-44, with the maximum in the range of 7.5-9.6 microns. Histograms, built according to the space occupied by lymphoid cells, evidenced that in malignant thyroid disease a cupola-shaped character of distribution was peculiar, whereas in other pathologies and in norm the exponential relationship was revealed.

摘要

通过对甲状腺活检和尸检样本的触摸涂片进行淋巴细胞、原淋巴细胞和淋巴母细胞的细胞计数分析,发现在癌症中,这些淋巴细胞总数中的小淋巴细胞占0 - 2%,并且在淋巴细胞分布直方图上,根据平均直径,最大值在9.6 - 11.7微米范围内。在良性畸形、甲状腺肿和自身免疫性甲状腺炎以及正常情况下,小淋巴细胞的百分比在10 - 44范围内变化,最大值在7.5 - 9.6微米范围内。根据淋巴细胞所占空间构建的直方图表明,在甲状腺恶性疾病中,分布呈圆顶状是其特点,而在其他病理情况和正常情况下则呈现指数关系。

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