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[甲状腺癌患者针吸活检样本中淋巴细胞群体的细胞计数评估]

[Cytometric estimation of lymphoid cell population in needle biopsy samples from patients with thyroid cancer].

作者信息

Kirillov V A, Iushchenko I P

出版信息

Vopr Onkol. 1996;42(3):22-5.

PMID:8801735
Abstract

Fine-needle aspiration cytological examination has established the small lymphocyte fraction in the total population of lymphoid cells in thyroid cancer patients to be at 0-2%, the frequency peak for lymphoid cells of an average size as shown on histographs being located in the 3rd interval. In follicular adenoma, cyst, autoimmune thyroiditis and goiter, the small lymphocyte percentage was found to rise to 9-20%, the frequency peak shifting to the 2nd interval. The lymphoid cells area distribution pattern for cancer was of a domed shape while an exponential relationship was observed in the other pathologies. The newly-developed criteria for thyroid cancer diagnosis are expected to increase the effectiveness and predictive value of aspiration technique by 25%.

摘要

细针穿刺细胞学检查已确定甲状腺癌患者淋巴细胞总数中的小淋巴细胞比例为0 - 2%,组织学图谱显示平均大小的淋巴细胞频率峰值位于第3区间。在滤泡性腺瘤、囊肿、自身免疫性甲状腺炎和甲状腺肿中,小淋巴细胞百分比上升至9 - 20%,频率峰值移至第2区间。癌症的淋巴细胞面积分布模式呈穹顶状,而在其他病理情况下则观察到指数关系。新制定的甲状腺癌诊断标准有望使穿刺技术的有效性和预测价值提高25%。

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[Cytologic diagnosis of thyroid lesions by fine needle aspiration].
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