[聚二氧六环酮和蚕丝对手术损伤心肌组织正常瘢痕形成的影响。实验模型]

[Effects of polydioxanone and silk on normal cicatrisation of surgically injured myocardial tissue. An experimental model].

作者信息

Serrano-Gallardo G, Santibáñez Escobar F, Amansio Chassín O, Uribe Uribe N, Rojero Vallejo J, Olvera Nevárez R

机构信息

Departamento de Cirugía, Instituto Nacional de Cardiología Ignacio Chávez, México, D.F.

出版信息

Arch Inst Cardiol Mex. 1996 Jan-Feb;66(1):23-8.

PMID:8768618

Abstract

The wound healing is the principal process of tissue repair. In the heart this phenomenon is done under special circumstances, because of the constant movement of this organ. An experimental study was done in 15 dogs. By left anterolateral thoracotomy the free left ventricular wall was incised. This incision was done 1 cm long and 3 mm deep and afterwards it was repaired with silk (Group I) and with polydioxanone (Group II). The wound was allowed to heal during 5 weeks, then the scar area was analyzed by light microscope with Masson and HE technics. The results showed the presence of lymphocytes in the scar tissue of group II (p = 0.04).

摘要

伤口愈合是组织修复的主要过程。在心脏中，由于该器官的持续运动，这种现象是在特殊情况下进行的。对15只狗进行了一项实验研究。通过左前外侧开胸术切开左心室游离壁。该切口长1厘米、深3毫米，然后分别用丝线（第一组）和聚二氧六环酮（第二组）进行修复。让伤口在5周内愈合，然后用Masson染色法和苏木精-伊红染色法通过光学显微镜分析瘢痕区域。结果显示，第二组瘢痕组织中有淋巴细胞存在（p = 0.04）。