Coetzee A, Rousseau H, Lahner D
Department of Anaesthesiology, University of Stellenbosch, Tygerberg, W. Cape.
S Afr Med J. 1996 Jun;86 Suppl 3:C147-51.
The severity of acute pulmonary hypertension (APHT) in acute respiratory distress syndrome was examined in 20 patients. All patients had significant APHT (mean pressure 40.6 +/- 6.3 mmHg) on admission to the intensive care unit. There was evidence of right ventricular (RV) failure, with a right ventricular stroke work index (RVSWI) of 9.20 +/- 3.3 g.m/m2 and a central venous pressure of 18.0 +/- 4.0 mmHg. The RV afterload, i.e. pulmonary artery elastance (Ea = stroke volume/peak pulmonary artery pressure), was raised. Stroke volume could not be predicted from Ea or RVSWI alone, but regression analysis indicated that the ratio of RVSWI/Ea (i.e. ventriculo-arterial coupling) could account for 88% of the stroke volume.
对20例急性呼吸窘迫综合征患者的急性肺动脉高压（APHT）严重程度进行了检查。所有患者在入住重症监护病房时均有显著的APHT（平均压力40.6±6.3 mmHg）。有右心室（RV）衰竭的证据，右心室每搏功指数（RVSWI）为9.20±3.3 g.m/m2，中心静脉压为18.0±4.0 mmHg。右心室后负荷，即肺动脉弹性（Ea = 每搏量/肺动脉峰值压力）升高。仅根据Ea或RVSWI无法预测每搏量，但回归分析表明，RVSWI/Ea比值（即心室动脉耦合）可解释88%的每搏量。
