Dept of Pulmonology, Institute for Cardiovascular Research VU University Medical Center, VU University, Amsterdam, The Netherlands.
Eur Respir J. 2013 Jun;41(6):1419-23. doi: 10.1183/09031936.00160712. Epub 2013 Jan 11.
In pulmonary hypertension and other conditions, such as acute respiratory distress syndrome and left heart failure, right ventricular dysfunction is a prognostic determinant. Therefore, functional parameters pertaining to the right heart alone, i.e. independent of its loading conditions, should be used to quantify right ventricular disease progression and the results of treatment. Two methods to quantitatively describe right ventricular function are reviewed, the pressure-volume relationship and the pump function graph; examples of each method are given. How to estimate wall stress and how to describe diastolic ventricular properties are also discussed.
在肺动脉高压和其他疾病中,如急性呼吸窘迫综合征和左心衰竭,右心室功能障碍是一个预后决定因素。因此,应该使用与右心有关的功能参数,即不依赖于其负荷条件的参数,来定量评估右心室疾病的进展和治疗效果。本文回顾了两种定量描述右心室功能的方法,即压力-容积关系和泵功能图,并给出了每种方法的示例。还讨论了如何估计壁应力以及如何描述舒张期心室特性。