精神分裂症和精神病性抑郁症中阴性、阳性及抑郁症状之间的关系。
Relationships among negative, positive, and depressive symptoms in schizophrenia and psychotic depression.
作者信息
Sax K W, Strakowski S M, Keck P E, Upadhyaya V H, West S A, McElroy S L
机构信息
Department of Psychiatry, University of Cincinnati College of Medicine, Ohio 45267-0559, USA.
出版信息
Br J Psychiatry. 1996 Jan;168(1):68-71. doi: 10.1192/bjp.168.1.68.
BACKGROUND
We examined relationships among positive, negative, and depressive symptoms in schizophrenia and major depression with psychosis.
METHOD
Patients with schizophrenia (n = 17) and major depression and psychotic features (n = 25), with no prior psychopharmacologic treatment were assessed on scales measuring positive psychotic, negative, and depressive symptoms.
RESULTS
Analyses revealed the depressive symptoms positively correlated with anhedonia/asociality and avolition/apathy in both patient groups. Positive psychotic symptoms significantly correlated with depressive symptoms in the schizophrenic group.
CONCLUSIONS
Several specific symptoms used in defining both depressive and negative syndrome constructs appear to be shared. The relationship between positive symptoms and depression in schizophrenia and not psychotic depression suggests the severity of depression may be involved in this relationship.
背景
我们研究了精神分裂症以及伴有精神病性症状的重度抑郁症中阳性、阴性和抑郁症状之间的关系。
方法
对17例精神分裂症患者和25例伴有精神病性特征的重度抑郁症患者进行评估，这些患者之前均未接受过精神药物治疗，评估采用测量阳性精神病性、阴性和抑郁症状的量表。
结果
分析显示，两组患者的抑郁症状均与快感缺失/社交障碍以及意志缺乏/淡漠呈正相关。精神分裂症组中，阳性精神病性症状与抑郁症状显著相关。
结论
用于定义抑郁综合征和阴性综合征的一些特定症状似乎是相同的。精神分裂症而非精神病性抑郁症中阳性症状与抑郁之间的关系表明，抑郁的严重程度可能与这种关系有关。
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