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沙特儿童中由弓形虫病导致的感音神经性听力损失患病率:一项基于医院的研究。

Prevalence of sensorineural hearing loss due to toxoplasmosis in Saudi children: a hospital based study.

作者信息

al Muhaimeed H

机构信息

Department of Otorhinolaryngology, King Abdul Aziz University Hospital, Riyadh, Saudi Arabia.

出版信息

Int J Pediatr Otorhinolaryngol. 1996 Jan;34(1-2):1-8. doi: 10.1016/0165-5876(95)01223-0.

DOI:10.1016/0165-5876(95)01223-0
PMID:8770668
Abstract

A survey to identify the aetiology of hearing impairment among Saudi children was carried out. Children were divided into 2 groups according to presence or absence of laboratory evidence of toxoplasmosis "at risk' and "not at risk.' Serological tests for toxoplasmosis were done to 1054 children. We found positive IgM antibody against Toxoplasma gondii in the blood of 70 of the 1054 children (6.6%) (age ranged between 12 months and 14 years). Forty nine of the seventy infected children (70%) were found to have bilateral sensorineural hearing loss (11 of 19 children of the at risk group and 38 of 51 from the "not at risk' group). Hearing impairment was bilateral in all cases profound in 9, moderate to severe in 29 and mild in 11. Known causes of hearing impairment were excluded. The high prevalence of hearing impairment among children due to toxoplasmosis is presented.

摘要

一项旨在确定沙特儿童听力障碍病因的调查展开了。根据是否存在弓形虫病实验室证据,儿童被分为两组,即“有风险”组和“无风险”组。对1054名儿童进行了弓形虫病血清学检测。我们在1054名儿童中的70名(6.6%)(年龄在12个月至14岁之间)血液中发现了抗弓形虫的阳性IgM抗体。在这70名受感染儿童中,有49名(70%)被发现患有双侧感音神经性听力损失(有风险组的19名儿童中有11名,无风险组的51名儿童中有38名)。所有病例的听力障碍均为双侧性,其中9例为重度,29例为中度至重度,11例为轻度。排除了已知的听力障碍原因。本文呈现了因弓形虫病导致儿童听力障碍的高患病率。

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引用本文的文献

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Study of brainstem auditory evoked potentials in early diagnosis of congenital toxoplasmosis.脑干听觉诱发电位在先天性弓形虫病早期诊断中的研究
Braz J Otorhinolaryngol. 2019 Jul-Aug;85(4):447-455. doi: 10.1016/j.bjorl.2018.03.012. Epub 2018 Apr 22.
2
Toxoplasmosis--a global threat. Correlation of latent toxoplasmosis with specific disease burden in a set of 88 countries.弓形虫病——全球威胁。88个国家中潜伏性弓形虫病与特定疾病负担的相关性。
PLoS One. 2014 Mar 24;9(3):e90203. doi: 10.1371/journal.pone.0090203. eCollection 2014.
3
Hearing loss in congenital toxoplasmosis detected by newborn screening.
通过新生儿筛查检测先天性弓形虫病中的听力损失。
Braz J Otorhinolaryngol. 2008 Jan-Feb;74(1):21-8. doi: 10.1016/s1808-8694(15)30746-1.