Motarjeme A, Gordon G I, Bodenhagen K
Midwest Vascular Institute, Downers Grove, IL 60515, USA.
J Vasc Interv Radiol. 1995 Nov-Dec;6(6 Pt 2 Suppl):66S-72S. doi: 10.1016/s1051-0443(95)71251-9.
The role of percutaneous angioplasty in the management of chronic iliac artery occlusions is controversial. This article reviews 7 years of experience in treating patients with complete chronic iliac artery occlusions (n = 99) by using thrombolysis and angioplasty. Patients were not excluded due to age or length of the lesion, or severity of underlying peripheral vascular disease. Thrombolysis was conducted with infusion of urokinase at a rate of 60,000-80,000 IU/h for 24 hours. Angioplasty was then performed irrespective of the results of thrombolysis. Seventy-nine percent of patients responded to urokinase, with complete lysis achieved in 55%. Angioplasty was successful in all patients with complete thrombolysis and in 88% of those with partial thrombolysis. The overall success rate was 86%, and more than 80% of surviving patients were symptom free at 5 years. There were seven complications, and the 30-day mortality rate was 2%. Our present results confirm the efficacy of thrombolysis/angioplasty for chronic arterial occlusions.
经皮血管成形术在慢性髂动脉闭塞治疗中的作用存在争议。本文回顾了7年中使用溶栓和血管成形术治疗99例完全性慢性髂动脉闭塞患者的经验。患者不因年龄、病变长度或潜在外周血管疾病的严重程度而被排除。以60,000 - 80,000 IU/h的速率输注尿激酶进行24小时溶栓。然后无论溶栓结果如何均进行血管成形术。79%的患者对尿激酶有反应，55%实现了完全溶解。血管成形术在所有完全溶栓的患者以及88%部分溶栓的患者中获得成功。总体成功率为86%，超过80%的存活患者在5年时无症状。发生了7例并发症，30天死亡率为2%。我们目前的结果证实了溶栓/血管成形术治疗慢性动脉闭塞的有效性。
