Knezevic V
Institute of Biology, School of Medicine, University of Zagreb, Republic of Croatia.
J Anat. 1996 Aug;189 ( Pt 1)(Pt 1):1-7.
The differentiation potential of rat amnion was investigated by explantation to different extrauterine sites and by culturing in vitro. Amnion differentiated into full skin by a process that is morphologically indistinguishable from normal skin development (interactions of the surface embryonic ectoderm and underlying mesenchyme). This process is not dependent on the age of the amnion but is dependent on the culture conditions used. Possible implications of these findings are discussed.
通过将大鼠羊膜移植到不同的子宫外部位并进行体外培养,研究了其分化潜能。羊膜通过一个在形态上与正常皮肤发育(表面胚胎外胚层和下方间充质的相互作用)无法区分的过程分化为完整的皮肤。这个过程不依赖于羊膜的年龄,而是依赖于所使用的培养条件。讨论了这些发现可能的意义。