[The function of the hypophyseal-adrenal and hypophyseal-thyroid systems in patients with hemorrhagic fever with renal syndrome].

Hypophyseo-adrenal and hypophyseo-thyroid systems were studied in 102 patients aged 16-55 (88 males and 14 females) who suffered from hemorrhagic fever with renal syndrome. Measurements of serum levels of ACTH, hydrocortisone, TTH, T3 and T4 recorded supernormal concentrations of ACTH, hydrocortisone and TTH against subnormal concentrations of T3 and T4 in oliguric and polyuric periods of the disease. In convalescence TTH, T3 and T4 returned to normal levels, while ACTH and hydrocortisone were lower than in controls. It is inferred that in hemorrhagic fever with renal syndrome the activity of the system hypophysis-adrenals in convalescence is declined, whereas hypophysis-thyroid interaction is disturbed at the height of the disease.