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[急性肺炎患者垂体-肾上腺和垂体-甲状腺系统的紊乱及其治疗纠正方法]

[Disorders in the hypophysis-adrenal and hypophysis-thyroid systems of patients with acute pneumonia and the ways for their therapeutic correction].

作者信息

Panfilov Iu A, Sharonov V G

出版信息

Ter Arkh. 1990;62(3):19-22.

PMID:2367990
Abstract

Using RIA, 188 patients with acute pneumonia were examined over time for the blood ACTH, cortisol, TTH, T3 and T4 content as well as for T4/T3, TTH/T3 and TTH/T4 correlations. Under discussion are causes, approaches to the prevention and correction of the hormonal disorders revealed in the pituitary-adrenal system in patients with an unfavourable course of pneumonia. The majority of the patients manifested thyroid hypofunction and TTH hypersecretion, which remained unchanged even during the clinical recovery, since the first days of the disease. It is advisable that microdoses of thyroidine may be included into the multimodality treatment of patients afflicted with acute pneumonia and iodine-containing expectorants excluded from it.

摘要

采用放射免疫分析法,对188例急性肺炎患者的血液促肾上腺皮质激素(ACTH)、皮质醇、促甲状腺素(TTH)、三碘甲状腺原氨酸(T3)和甲状腺素(T4)含量以及T4/T3、TTH/T3和TTH/T4相关性进行了长期检测。文中讨论了肺炎病情不利的患者垂体 - 肾上腺系统中所发现的激素紊乱的成因、预防和纠正方法。大多数患者表现出甲状腺功能减退和促甲状腺素分泌过多,自疾病发作的第一天起,即使在临床康复期间这些症状仍未改变。建议在急性肺炎患者的多模式治疗中加入小剂量甲状腺素,并排除含碘祛痰剂。

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