Petrovskaia V G, Marakusha B I, Bondarenko V M
Zh Mikrobiol Epidemiol Immunobiol. 1996 May-Jun(3):25-8.
The presently known methods of obtaining Salmonella vaccine strains are characterized, their advantages and drawbacks are noted. Great importance of the genetic safety of Salmonella attenuated strains to be controlled is emphasized, taking into account that they are also used as carrier strains for obtaining hybrid and gene-engineering (vector) vaccines carrying immunogenicity factors of other species of pathogenic microorganisms.
对目前已知的获取沙门氏菌疫苗株的方法进行了特征描述,指出了它们的优缺点。强调了对减毒沙门氏菌菌株进行遗传安全性控制的重要性,因为它们还被用作载体菌株,用于获取携带其他致病微生物物种免疫原性因子的杂交疫苗和基因工程(载体)疫苗。