Ko T, Tada H, Hatoko M, Muramatsu T, Shirai T
Department of Dermatology, Nara Medical University, Japan.
J Dermatol. 1996 Jul;23(7):463-8.
Two cases of trichilemmal carcinoma (TLC) developing in burn scars are reported. In Case 1, a 73-year-old man developed a TLC on his left lower leg five years after a burn. In Case 2, a 43-year-old man developed a cauliflower-like mass on his head 42 years after a burn. Histologically, tumor cells showed a lobular proliferation in continuity with the epidermis. Tumor nests were mostly composed of large atypical cells with clear cytoplasms containing PAS-positive, diastase sensitive materials. Some of the nests showed trichilemmal-type keratinization. These cases were treated only with surgical excision, and there has been no evidence since of local recurrence or metastasis.
报告了两例在烧伤瘢痕中发生的毛鞘癌(TLC)。病例1,一名73岁男性在烧伤五年后左小腿出现毛鞘癌。病例2,一名43岁男性在烧伤42年后头部出现菜花状肿物。组织学上,肿瘤细胞呈小叶状增生,与表皮连续。肿瘤巢主要由大的非典型细胞组成,细胞质清晰,含有PAS阳性、淀粉酶敏感物质。部分巢显示毛鞘型角化。这些病例仅接受了手术切除治疗,此后没有局部复发或转移的证据。