Gahmberg C G, Tolvanen M
Department of Biosciences, University of Helsinki, Finland.
Trends Biochem Sci. 1996 Aug;21(8):308-11.
Most proteins presented at the external surface of mammalian cells contain carbohydrate. The reason for this is not fully understood, but recent work has shown that such carbohydrate has two major functions. Inside the cell, it helps proteins fold and assembly correctly in the endoplasmic reticulum, and it might also act as a signal for the correct migration of glycoproteins. Outside the cell, it provides specific recognition structures for interaction with a variety of external ligands.
大多数存在于哺乳动物细胞外表面的蛋白质都含有碳水化合物。其原因尚未完全明确，但最近的研究表明，这种碳水化合物具有两大主要功能。在细胞内部，它有助于蛋白质在内质网中正确折叠和组装，并且可能还作为糖蛋白正确迁移的信号。在细胞外部，它为与各种外部配体的相互作用提供特定的识别结构。
