Narang A, Nair P M, Bhakoo O N, Vashisht K
Department of Pediatrics, PGIMER, Chandigarh.
Indian Pediatr. 1993 Jan;30(1):9-13.
Passage of meconium in utero is a serious neonatal disorder carrying high morbidity and mortality. Role of planned team approach with aggressive intrapartum suctioning and intensive neonatal management was studied to evaluate its impact on neonatal morbidity and mortality. Meconium Stained Amniotic Fluid (MSAF) was found amongst 7.4% of all deliveries and among these 238 (10.5%) babies developed meconium aspiration syndrome (MAS). Ninety five per cent babies with MSAF were born at > 36 weeks of gestation and 76% were more than 2.5 kg. Passage of thick and thin meconium was seen in 44 and 56% respectively. Passage of thick meconium was significantly associated with severe asphyxia and carried a bad prognosis with increased risk of development of meconium aspiration syndrome, hypoxic schemic encephalopathy, seizures and pulmonary air leak syndrome. Aggressive team approach was responsible for lowering the mortality to 7.7%.
胎儿宫内排胎便是一种严重的新生儿疾病,发病率和死亡率都很高。本研究探讨了采用有计划的团队协作方法、积极的产时吸引及强化新生儿管理,以评估其对新生儿发病率和死亡率的影响。在所有分娩中,7.4%发现有胎粪污染羊水(MSAF),其中238例(10.5%)婴儿发生了胎粪吸入综合征(MAS)。95%有MSAF的婴儿在妊娠>36周时出生,76%体重超过2.5kg。分别有44%和56%的病例出现了浓稠和稀薄胎粪排出。浓稠胎粪排出与严重窒息显著相关,预后不良,发生胎粪吸入综合征、缺氧缺血性脑病、癫痫和肺空气泄漏综合征的风险增加。积极的团队协作方法使死亡率降至7.7%。