Sigge W
Department of Pediatric Surgery, Medical University of Lübeck, Germany.
Eur J Pediatr Surg. 1995 Dec;5(6):327-37. doi: 10.1055/s-2008-1066237.
Young female beagles underwent either 85% resection of the small intestine; simultaneous 85% resection and patching of incised ideal remnant with colon serosa or with muscularis propria from transposed colon; or muscularis propria patching of ileum without resection of the small intestine. Patch areas were created in antiperistaltic position of participating bowel loops. After 20 weeks 50% of serosal patch and 34% of muscularis propria patch were overgrown by neomucosa. After 40 weeks 75% of the serosal patch was covered by neomucosa. Serosal patch area at necropsy 20 weeks after 85% resection of small intestine was 60% of the initial size; muscularis propria patch showed 44% of its primary area, but was only 12% of the initial surface area without bowel resection. Increases in resorptive surface consisted of neomucosa and an impressive adaptive elongation of short bowel, that was intensified by the simultaneous growth of the neomucosa.
小肠85%切除术；同时进行85%小肠切除术，并将切开的理想残余肠段用结肠浆膜或转位结肠的固有肌层进行修补；或在不切除小肠的情况下用固有肌层修补回肠。在参与手术的肠袢的逆蠕动位置创建修补区域。20周后，50%的浆膜修补处和34%的固有肌层修补处被新黏膜覆盖。40周后，75%的浆膜修补处被新黏膜覆盖。在小肠85%切除术后20周尸检时，浆膜修补面积为初始大小的60%；固有肌层修补处显示其原始面积的44%，但在未进行肠切除的情况下仅为初始表面积的12%。吸收表面的增加包括新黏膜和短肠令人印象深刻的适应性延长，新黏膜的同时生长加剧了这种延长。
