Polycystic ovary syndrome: clinical aspects.

The clinical presentation of PCOS is likely to be the end process of many pathogenic mechanisms, the definition of which is only now beginning to be unravelled. While the application of ultrasonography to the diagnosis of PCOS has undoubtedly added greatly to our understanding of the breadth of the disorder and our appreciation of its heterogeneity, careful distinction has to be made between polycystic ovaries and polycystic ovary syndrome in order to define optimal treatments, particularly in women with menstrual disturbance. In the presence of obesity, no treatment regimen can neglect weight reduction as the main thrust of intervention, no matter whether the goal be to improve hirsutism or infertility.