Hoppe M, Wagner H J, Klose K J
Department of Diagnostic Radiology, University Hospital, Marburg, Germany.
J Vasc Interv Radiol. 1996 Jan-Feb;7(1):89-93. doi: 10.1016/s1051-0443(96)70739-x.
To determine the usefulness of a Doppler guide wire for assessing the hemodynamic results of balloon dilation of atherosclerotic arterial obstruction.
A 0.018-inch 12-MHz Doppler guide wire was used to measure the maximum peak velocity and the time-averaged peak velocity (APV) proximal to, inside, and distal to lesions in 10 consecutively seen patients (six men, four women; mean age, 68 years +/- 11 [standard deviation]). Measurements were made before and after percutaneous transluminal angioplasty (PTA).
The proximal-to-intrastenotic APV ratio was the best predictor of the grade of residual stenosis and correlated well with angiographic measurements (r = .8). Balloon dilation resulted in a significant increase in mean APV distal to the obstruction (12.5 cm/sec before versus 27.6 cm/sec after PTA; P < .05). The mean proximal-to-distal APV ratio also decreased significantly (3.7 before versus 1.0 after PTA; P < .005).
The Doppler guide wire can be used for direct intravascular evaluation of the result of balloon dilation in atherosclerotic obstructions.
