Brink E J, Haddeman E, Tijburg L B
Unilever Research Laboratory, Vlaardingen, The Netherlands.
Br J Nutr. 1996 Jun;75(6):939-48. doi: 10.1079/bjn19960199.
Vegetable fats and oils are major sources of dietary vitamin E. Consequently the current trend to reduce fat consumption is accompanied by a reduction of the intake of vitamin E. In addition, the absorption of vitamin E is thought to be dependent on the hydrolysis of dietary lipids in the small intestine. It is therefore conceivable that a lower dietary fat intake also diminishes the intestinal absorption of vitamin E. The present 3-week feeding study in young male rats was designed to investigate whether different concentrations of vitamin E added to a very-low-fat product (0, 330 or 1350 mg DL-alpha-tocopheryl acetate/kg product) were absorbed. We therefore incorporated these products into a very-low-fat meal (final fat concentration: 7 g/kg) or a low-fat meal containing 52 g fat/kg. The magnitude of vitamin E absorption from these meals was compared with that from meals containing similar amounts of vitamin E, but a high fat concentration of 190 g/kg. Apparent vitamin E absorption was defined as intake of alpha-tocopherol equivalents (alpha TE) minus faecal alpha TE excretion over 4 d during week 3 of the experimental period. The results of this study showed that apparent absorption of vitamin E from a very-low-fat meal varied, depending on the vitamin E concentration, from 73 to 83%. The magnitude of this vitamin E absorption was not significantly different from that from meals containing a high amount of fat. Liver vitamin E status was equal in rats fed on the very-low-fat meals compared with those fed on the high-fat meals. We conclude that, when very-low-fat or low-fat products are used as a replacement for full-fat products, addition of vitamin E to these products, as DL-alpha-tocopheryl acetate, might be useful in meeting the vitamin E requirements.
植物油脂是膳食中维生素E的主要来源。因此，当前减少脂肪摄入的趋势伴随着维生素E摄入量的减少。此外，维生素E的吸收被认为依赖于小肠中膳食脂质的水解。因此可以想象，较低的膳食脂肪摄入量也会减少维生素E的肠道吸收。本项针对年轻雄性大鼠进行的为期3周的喂养研究旨在调查添加到极低脂肪产品（0、330或1350 mg DL-α-生育酚乙酸酯/千克产品）中的不同浓度的维生素E是否能被吸收。因此，我们将这些产品添加到极低脂肪餐（最终脂肪浓度：7克/千克）或含有52克脂肪/千克的低脂餐中。将这些餐中维生素E的吸收量与含有相似量维生素E但脂肪浓度为190克/千克的餐中的吸收量进行比较。表观维生素E吸收定义为实验期第3周4天内α-生育酚当量（α-TE）的摄入量减去粪便中α-TE的排泄量。本研究结果表明，极低脂肪餐中维生素E的表观吸收量因维生素E浓度而异，在73%至83%之间。这种维生素E吸收量与高脂肪餐中的吸收量没有显著差异。与喂食高脂肪餐的大鼠相比，喂食极低脂肪餐的大鼠肝脏维生素E水平相当。我们得出结论，当使用极低脂肪或低脂产品替代全脂产品时，向这些产品中添加作为DL-α-生育酚乙酸酯的维生素E可能有助于满足维生素E的需求。
