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骨质疏松症的进展:更好地识别风险因素可降低发病率和死亡率。

Advances in osteoporosis: better identification of risk factors can reduce morbidity and mortality.

作者信息

Johnell O

机构信息

Department of Orthopaedics, Malmõ General Hospital, Sweden.

出版信息

J Intern Med. 1996 Apr;239(4):299-304. doi: 10.1046/j.1365-2796.1996.429781000.x.

Abstract

Osteoporosis is a common disease of postmenopausal women and the elderly. Low bone mass results from genetic, nutritional and lifestyle factors, decreased oestrogen levels, certain medical conditions, and the use of certain drugs. The overall incidence and age- and sex-related incidences of osteoporosis are increasing worldwide. Osteoporotic fractures can cause considerable pain, disability, loss of independence and deterioration in quality of life. Many patients lose the ability to perform the activities of daily living. Mortality and morbidity after hip fracture increase with age. Prevention of osteoporosis and osteoporotic fractures is an urgent priority to reduce the burden placed on health care and social welfare systems.

摘要

骨质疏松症是绝经后女性和老年人的常见疾病。低骨量由遗传、营养和生活方式因素、雌激素水平降低、某些医疗状况以及某些药物的使用导致。全球范围内,骨质疏松症的总体发病率以及与年龄和性别相关的发病率都在上升。骨质疏松性骨折可导致相当程度的疼痛、残疾、失去独立生活能力以及生活质量下降。许多患者丧失了进行日常生活活动的能力。髋部骨折后的死亡率和发病率随年龄增长而增加。预防骨质疏松症和骨质疏松性骨折是减轻医疗保健和社会福利系统负担的当务之急。

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