Farsi H M, Mosli H A, Al-Zemaity M F, Bahnassy A A, Alvarez M
Department of Urology, King Abdulaziz University Hospital, Jeddah, Saudi Arabia.
J Endourol. 1995 Dec;9(6):469-72. doi: 10.1089/end.1995.9.469.
We prospectively studied 266 patients with indwelling double-pigtail ureteral stents to determine the incidence of stent colonization and associated bacteriuria. A urine culture was obtained just prior to stent insertion and was repeated at the time of its removal. The stent itself was also cultured. Of the 237 evaluable patients, 71 (29.9%) developed bacteriuria. Of the 237 stents, 161 (67.9%) became colonized with microorganisms. Pseudomonas aeruginosa was the most common pathogen isolated from the urine and the stents. Stents in female patients had a higher rate of colonization than those used in males (74.4% v 66.5%). The longer the duration of stenting, the higher was the rate of colonization (58.6% for stents left for < 1 month v 75.1% for those left for > 3 months). The rate of colonization according to catheter type was as follows: C-flex 55.5%, silicone 62.6%, urethane 100%, and Urosoft 56%. Long-term ureteric stenting is associated with a high rate of bacteriuria and stent colonization. The duration of stenting and the type of stent influence the results. We recommend that patients with double-J ureteral stents who could be at risk from bacteremia be covered by appropriate antibiotics, and the stents should be kept indwelling for the shortest possible time. If a patient with a stent develops symptomatic infection, an antibiotic should be started that covers the Pseudomonas species.
我们前瞻性地研究了266例留置双猪尾输尿管支架的患者,以确定支架定植及相关菌尿的发生率。在支架置入前获取尿培养样本,并在取出支架时重复进行。同时也对支架本身进行培养。在237例可评估患者中,71例(29.9%)发生了菌尿。在237个支架中,161个(67.9%)被微生物定植。铜绿假单胞菌是从尿液和支架中分离出的最常见病原体。女性患者的支架定植率高于男性患者(74.4%对66.5%)。支架留置时间越长,定植率越高(留置时间<1个月的支架为58.6%,留置时间>3个月的支架为75.1%)。根据导管类型的定植率如下:C-flex为55.5%,硅胶为62.6%,聚氨酯为100%,Urosoft为56%。长期输尿管支架置入与高菌尿率和支架定植相关。支架留置时间和支架类型会影响结果。我们建议,可能有菌血症风险的双J输尿管支架患者应使用适当的抗生素,并且支架应尽可能缩短留置时间。如果带支架的患者发生有症状感染,应开始使用覆盖假单胞菌属的抗生素。