Teegarden D, Proulx W R, Kern M, Sedlock D, Weaver C M, Johnston C C, Lyle R M
Department of Foods and Nutrition, Purdue University, Indiana University Medical Center, Indianapolis, USA.
Med Sci Sports Exerc. 1996 Jan;28(1):105-13. doi: 10.1097/00005768-199601000-00021.
Exercise may increase accretion of bone, potentially reducing the risk of osteoporosis. Previous physical activity was assessed in 204 minimally active young women (18-31 yr). Bone mineral content (BMC) and bone mineral density (BMD) for the total body, femoral neck, and spine were assessed by a dual x-ray absorptiometer, and the radius by a single photon absorptiometer. Self-reported occupation and leisure activity for the 5 yr before enrollment in the study, as well as high school and college sports participation, were assigned energy expenditure (EE) values. From this information, EE variables were created as follows: 1) occupation EE + leisure EE + high school sport and/or college sport EE if within prior 5 yr (5-yr EE); 2) occupation EE + leisure EE (occupation + leisure EE); and 3) high school sport EE (high school EE). These variables were correlated with bone mineral measures and significant results follow (P < 0.05). Five-year EE and occupation + leisure EE correlated with all measures of bone health (r from 0.13 to 0.39). High school EE correlated with total body BMD (r = 0.25) and BMC (r = 0.28), femoral neck BMD (r = 0.28), radius BMC (r = 0.20), as well as spine BMD (r = 0.20) and BMC (r = 0.27). When weight was controlled, 5-yr EE and occupation + leisure EE remained correlated with all BMC measures (r from 0.14 to 0.22). When controlled for weight, high school EE remained associated with femoral neck BMD (r = 0.24), total body BMD (r = 0.20) and BMC (r = 0.26), and spine BMC (r = 0.17). To partially control for selection bias, data were also controlled for total body BMD. Five-year EE and occupation + leisure EE remained positively correlated with all measures of BMC. High school EE remained correlated both with femoral neck BMD and total body BMC. In multiple regression analyses, 5-yr EE or occupation + leisure EE were significant predictors of all measures of bone health, except femoral neck BMD. High school EE was a significant predictor for total body BMD and BMC, femoral neck BMD, and spine BMC.
运动可能会增加骨质积累，从而潜在地降低患骨质疏松症的风险。对204名轻度活跃的年轻女性（18 - 31岁）的既往身体活动情况进行了评估。通过双能X线吸收仪评估全身、股骨颈和脊柱的骨矿物质含量（BMC）和骨矿物质密度（BMD），通过单光子吸收仪评估桡骨。根据研究入组前5年的自我报告职业和休闲活动以及高中和大学的体育参与情况，赋予能量消耗（EE）值。根据这些信息，创建了如下EE变量：1）如果在之前5年内，则为职业EE + 休闲EE + 高中体育和/或大学体育EE（5年EE）；2）职业EE + 休闲EE（职业 + 休闲EE）；3）高中体育EE（高中EE）。这些变量与骨矿物质测量值相关，结果如下（P < 0.05）。5年EE和职业 + 休闲EE与所有骨骼健康指标相关（r值范围为0.13至0.39）。高中EE与全身BMD（r = 0.25）、BMC（r = 0.28）、股骨颈BMD（r = 0.28）、桡骨BMC（r = 0.20）以及脊柱BMD（r = 0.20）和BMC（r = 0.27）相关。在控制体重后，5年EE和职业 + 休闲EE仍与所有BMC指标相关（r值范围为0.14至0.22）。在控制体重后，高中EE仍与股骨颈BMD（r = 0.24）、全身BMD（r = 0.20）和BMC（r = 0.26）以及脊柱BMC（r = 0.17）相关。为了部分控制选择偏倚，数据还对全身BMD进行了控制。5年EE和职业 + 休闲EE仍与所有BMC指标呈正相关。高中EE仍与股骨颈BMD和全身BMC相关。在多元回归分析中，5年EE或职业 + 休闲EE是除股骨颈BMD外所有骨骼健康指标的显著预测因素。高中EE是全身BMD和BMC、股骨颈BMD以及脊柱BMC的显著预测因素。
