Kamyshev N G, Kamysheva E A, Ivanova G O
Pavlov Institute of Physiology of the Russian Acad. Sci., St. Petersburg.
Fiziol Zh Im I M Sechenova. 1995 Aug;81(8):69-73.
Collection of autosomal P-insertional mutant stocks with single P-element per genome was created in Drosophila melanogaster. The learning ability was tested in 64 homozygous P-inserts using the original paradigm of self-starting operant learning in a group situation. Normal flies placed in a group situation learned to suppress their activity to avoid punishment. The learning-deficient mutants failed to change adaptively their initial locomotor response to presence of other individuals. The ability to learn in other paradigms of the associative learning is now being investigated in these mutant stocks.
在黑腹果蝇中创建了每个基因组含有单个P元件的常染色体P插入突变体库。使用群体情境下自启动操作性学习的原始范式,对64个纯合P插入体的学习能力进行了测试。置于群体情境中的正常果蝇学会抑制自身活动以避免惩罚。学习缺陷型突变体未能根据其他个体的存在适应性地改变其初始运动反应。目前正在这些突变体库中研究它们在其他联想学习范式中的学习能力。