Sheth S G, Amarapurkar D N, Chopra K B, Mani S A, Mehta P J
Department of Internal Medicine, Gastroenterology and Radiology, T.N. Medical College, Bombay, India.
J Clin Gastroenterol. 1996 Jan;22(1):28-30. doi: 10.1097/00004836-199601000-00008.
Splenomegaly is obvious in portal hypertension, but controversy still exists over the relationship between splenic size or size of esophageal varices. Previous methods to assess spleen size are less accurate than ultrasonic estimation of spleen size by splenic volumetric index (SVI). In a prospective study, we evaluated 101 consecutive patients with portal hypertension for spleen size measured ultrasonically by SVI, presence and size of esophageal varices, and etiology of portal hypertension. A total of 219 age-matched controls were evaluated ultrasonically to define a normal SVI. Splenomegaly defined by 1 or 2 standard deviations of normal SVI had high accuracy in predicting portal hypertension, presence of esophageal varices, and provided a clue to the etiology of portal hypertension. However, there was no correlation between spleen size and size of esophageal varices.
脾肿大在门静脉高压症中很明显，但脾脏大小与食管静脉曲张大小之间的关系仍存在争议。以往评估脾脏大小的方法不如通过脾脏容积指数（SVI）进行超声脾脏大小估计准确。在一项前瞻性研究中，我们对101例连续性门静脉高压症患者进行了评估，通过SVI超声测量脾脏大小、食管静脉曲张的存在及大小，以及门静脉高压的病因。总共对219例年龄匹配的对照者进行了超声评估以确定正常的SVI。由正常SVI的1或2个标准差定义的脾肿大在预测门静脉高压症、食管静脉曲张的存在方面具有较高的准确性，并为门静脉高压症的病因提供了线索。然而，脾脏大小与食管静脉曲张大小之间没有相关性。
