Hutchinson A K, Palay D A, Grossniklaus H E
Department of ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA.
Cornea. 1996 Jul;15(4):427-30. doi: 10.1097/00003226-199607000-00013.
We examined the clinicopathologic findings in two sisters with pigmented conjunctival lesions. Slit-lamp examination showed bilateral, circumferential cystic pigmented perilimbal lesion and prominent lipid keratopathy. The pigmented lesions were examined via biopsy, and histologic and ultrastructural examination of the biopsy specimens showed secondary melanosis of numerous conjunctival epithelial inclusion cysts. The two sisters have familial bilateral perilimbal cystic benign melanosis with lipid keratopathy, an idiopathic condition that requires no further surgical management.
我们检查了两名患有色素沉着性结膜病变的姐妹的临床病理特征。裂隙灯检查显示双侧、环形、囊性色素沉着性角膜缘病变以及明显的脂质角膜病变。通过活检对色素沉着性病变进行了检查，活检标本的组织学和超微结构检查显示，众多结膜上皮包涵囊肿存在继发性黑变病。这两名姐妹患有伴有脂质角膜病变的家族性双侧角膜缘囊性良性黑变病，这是一种无需进一步手术治疗的特发性疾病。
