Wolff J E, Boos J, Krähling K H, Jürgens H
Department of Pediatric Oncology, University of Münster, FRG.
Klin Padiatr. 1996 Jul-Aug;208(4):190-2. doi: 10.1055/s-2008-1046472.
A case of a malignant childhood glioma is reported with tumor-progression after surgery and radiotherapy during chemotherapy with cisplatinum, vincristine and CCNU, that responded temporally to oral treatment with VP16 and trofosfamide. A Phase II study with this combination is suggested.
报告了一例儿童恶性胶质瘤病例,该病例在接受顺铂、长春新碱和洛莫司汀化疗期间,术后及放疗后出现肿瘤进展,口服依托泊苷和曲磷胺后肿瘤暂时缓解。建议对该联合用药方案进行II期研究。