Wolff J E, Boos J, Kühl J
Kinderkliniken der Universität Münster.
Klin Padiatr. 1996 Jul-Aug;208(4):193-6. doi: 10.1055/s-2008-1046473.
The German society for paediatric oncology and hematology starts a clinical study for the treatment of children with glioblastoma, multifocal astrocytoma grade 3, brain stem grade 3 astrocytoma and typical diffuse ponsglioma. Conventional fractionated radiotherapy (54 Gy) will follow surgery. Simultaneously an additional experimental treatment will be given. The experimental treatment study will change every second year and starts with oral trofosfamide 100 mg/m2/d and VP16 25 mg/m2/d.
德国儿科肿瘤学和血液学协会启动了一项针对胶质母细胞瘤、多灶性3级星形细胞瘤、脑干3级星形细胞瘤和典型弥漫性桥脑胶质瘤患儿的临床研究。常规分割放疗（54 Gy）将在手术后进行。同时将给予额外的实验性治疗。实验性治疗研究将每两年更换一次，开始时采用口服曲磷胺100 mg/m²/天和依托泊苷25 mg/m²/天。
