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精神分裂症患者服用抗精神病药物后出现的溢乳和高催乳素血症:发生率及病因

Galactorrhea and hyperprolactinemia in schizophrenic patients on neuroleptics: frequency and etiology.

作者信息

Windgassen K, Wesselmann U, Schulze Mönking H

机构信息

Klinik und Poliklinik für Psychiatrie, Westfälische Wilhelms-Universität, Münster, Germany.

出版信息

Neuropsychobiology. 1996;33(3):142-6. doi: 10.1159/000119265.

Abstract

The frequency of galactorrhea and the subjective response to it were investigated in 150 schizophrenic patients. The incidence rate was 14% and the prevalence rate 19%. The latency periods between start of neuroleptic medication and manifestation of galactorrhea were subject to substantial scatter, as were the prolactin values. Patients who had undergone neuroleptic relapse prevention prior to the index episode and/or had been pregnant were affected significantly more frequently by galactorrhea.

摘要

对150例精神分裂症患者的溢乳频率及其主观反应进行了调查。发病率为14%,患病率为19%。抗精神病药物开始使用至溢乳出现之间的潜伏期以及催乳素值均存在较大离散度。在本次发病前接受过抗精神病药物预防复发治疗和/或曾怀孕的患者,溢乳的发生率显著更高。

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