Kamoi K, Terasaki T, Kojima M, Naya Y, Watanabe H
Department of Urology, Kyoto Prefectural University of Medicine.
Nihon Hinyokika Gakkai Zasshi. 1996 Jul;87(7):992-6. doi: 10.5980/jpnjurol1989.87.992.
The frequency of hematuria and proteinuria was assessed in terms of the existence of glomerular disorders.
Fifty-five patients with asymptomatic microscopic hematuria, in whom no urological disorders were recognized, were used in this study. The frequency of hematuria and proteinuria was assessed by self-test of the first voided urine in the morning with urinary dipsticks for 7 consecutive days. Hematuria (proteinuria) was judged positive when reaction for hematuria (proteinuria) on a dipstick was 1+ or more, and negative when reaction was - or +/-. On the basis of self-test, the frequency of hematuria (proteinuria) was classified into 3 types as follows: Type C, positive hematuria (proteinuria) recognized continuously throughout 7 days; Type S, positive and negative hematuria (proteinuria) recognized sporadically; Type N, negative hematuria (proteinuria) recognized throughout 7 days. The results were evaluated in terms of the existence of glomerular disorders, as revealed by renal biopsy.
Self-tests were completed successfully in 53 (96%) out of 55 patients at the first attempt. Of these 55 patients 32 (58%) were Type C hematuria, 14 (26%) were Type S hematuria and 9 (16%) were Type N hematuria. The incidence of glomerular disorders was significantly higher in patients with Type C (81%, p < 0.0001) and Type S (71% p < 0.01) hematuria than those with Type N (0%) hematuria.
The presence of hematuria confirmed by self-test used in the present study was suggestive of glomerular disorders.
根据肾小球疾病的存在情况评估血尿和蛋白尿的发生率。
本研究纳入了55例无症状镜下血尿患者,这些患者未发现泌尿系统疾病。连续7天使用尿试纸对晨尿进行自检,以评估血尿和蛋白尿的发生率。当尿试纸上血尿(蛋白尿)反应为1+或更高时,判断血尿(蛋白尿)为阳性;当反应为 - 或+/-时,判断为阴性。根据自检结果,血尿(蛋白尿)的发生率分为以下3种类型:C型,连续7天均为阳性血尿(蛋白尿);S型,血尿(蛋白尿)呈散发性阳性和阴性;N型,连续7天均为阴性血尿(蛋白尿)。根据肾活检显示的肾小球疾病的存在情况对结果进行评估。
55例患者中有53例(96%)首次尝试时成功完成自检。在这55例患者中,32例(58%)为C型血尿,14例(26%)为S型血尿,9例(16%)为N型血尿。C型(81%,p < 0.0001)和S型(71%,p < 0.01)血尿患者的肾小球疾病发生率显著高于N型(0%)血尿患者。
本研究中通过自检确认的血尿提示存在肾小球疾病。