Loemba H, Beuzit Y, Makuwa M
Hôpital central des armées, Département de médecine, Brazzaville, Congo.
Sante. 1995 Sep-Oct;5(5):278-82.
Our objective was twofold: firstly to evaluate the impact of AIDS on the annual increase of tuberculosis morbidity in Brazzaville; and secondly, to show its consequences on the reduced availability of hospital beds for patients treated for diseases nonrelated to AIDS. This retrospective study included 541 tuberculosis patients who were treated from 1988 to 1992 in the Department of Medicine at the Military Central Hospital in Brazzaville. The serum of all patients was tested by ELISA and Western blots for the presence of HIV. HIV and tuberculosis coinfection were very frequent (more than 30% of all AIDS cases), particularly among young people (20-45 years old). Extrapulmonary tuberculosis cases (37%) have become almost as frequent as pulmonary tuberculosis forms (42.8%) among HIV positive patients, and the clinical picture is often atypical. Tuberculosis morbidity is increasing annually because of AIDS. The longer the tuberculosis patients with AIDS remain in the hospital, the fewer beds are available for other patients. For the public health programs against AIDS in developing countries, this is becoming an urgent problem to resolve.
其一,评估艾滋病对布拉柴维尔结核病年发病率增长的影响;其二,展示其对非艾滋病相关疾病患者可用病床减少的后果。这项回顾性研究纳入了1988年至1992年在布拉柴维尔军事中心医院内科接受治疗的541名结核病患者。对所有患者的血清进行酶联免疫吸附测定(ELISA)和免疫印迹法检测,以确定是否存在艾滋病毒。艾滋病毒和结核病合并感染非常常见(在所有艾滋病病例中超过30%),尤其是在年轻人(20至45岁)中。在艾滋病毒呈阳性的患者中,肺外结核病例(37%)几乎与肺结核形式(42.8%)一样常见,而且临床表现往往不典型。由于艾滋病,结核病发病率每年都在上升。艾滋病合并结核病患者在医院停留的时间越长,可供其他患者使用的病床就越少。对于发展中国家的艾滋病公共卫生项目来说,这正成为一个亟待解决的问题。