Robbs J V
Surg Gynecol Obstet. 1977 Aug;145(2):235-40.
It would seem that, during the early phase of healing of a sutured colonic wound in the rabbit when a single layer continuous suture is used, silk results in a significantly stronger wound when compared with polypropylene, polyglactin 910 and chromic catgut of the same gauge, 000. Although at 14 days after operation, no significant differences in wound strength are apparent there appears to be some weakening at 21 days after operation. This is most marked with absorbable sutures, especially polyglactin 910. The mechanism of this is uncertain but may well be at a biochemical level related to collagen maturation. The strength of the suture line bears no correlation whatever to the degree of acute inflammatory reaction or fibrosis excited by the suture material upon histologic examination.
在兔子结肠缝合伤口愈合的早期阶段，当使用单层连续缝合时，与相同规格（000）的聚丙烯、聚乙醇酸910和铬制肠线相比，丝线能使伤口明显更牢固。尽管术后14天时伤口强度无明显差异，但术后21天时似乎有一些减弱。这在可吸收缝线中最为明显，尤其是聚乙醇酸910。其机制尚不确定，但很可能在与胶原蛋白成熟相关的生化水平上。组织学检查显示，缝线处的强度与缝线材料引发的急性炎症反应或纤维化程度毫无关联。
