Wilson A F, Savariryan S, James N, Mukai D, Nishimura E
Department of Medicine, University of California Irvine, Orange 92668, USA.
Med Sci Sports Exerc. 1996 Apr;28(4):436-43. doi: 10.1097/00005768-199604000-00007.
We measured gas exchange variables such as oxygen uptake, carbon dioxide output, and lung diffusing capacity using noninvasive techniques almost simultaneous with assessment of cardiovascular variables such as pulmonary blood flow at several levels of treadmill exercise up to and including maximal capacity. We utilized a single breath exhalation technique for measurement of diffusing capacity and cardiac output and breath by breath methodology for evaluating oxygen uptake. The equipment required for these measurements--rapid gas analyzers, oximeters, on-line computation, and pneumatic valves--are well within the capabilities of many exercise laboratories and are not difficult to use with subjects even at the heaviest levels of exercise. The results agreed well with values reported in the literature. From these entirely noninvasive measures, we calculated mixed venous oxygen saturation and maximal tissue oxygen diffusing capacity.
我们使用非侵入性技术测量了气体交换变量，如摄氧量、二氧化碳排出量和肺扩散容量，几乎与在跑步机上几个运动水平直至包括最大运动能力时对心血管变量（如肺血流量）的评估同时进行。我们采用单次呼气技术测量扩散容量和心输出量，并采用逐次呼吸法评估摄氧量。这些测量所需的设备——快速气体分析仪、血氧计、在线计算设备和气动阀——许多运动实验室都完全具备使用能力，并且即使在受试者进行最剧烈运动时也不难使用。结果与文献报道的值非常吻合。通过这些完全非侵入性的测量，我们计算出了混合静脉血氧饱和度和最大组织氧扩散容量。
