Säbel M, Aichinger H
Frauenklinik, Universität Erlangen-Nürnberg, Germany.
Phys Med Biol. 1996 Mar;41(3):315-68. doi: 10.1088/0031-9155/41/3/001.
A review of breast imaging has already appeared in 1982 in this journal. Consequently, the present article concentrates on a discussion of only those developments of a more recent nature. Although the emphasis is placed on the physical aspects of the different imaging methods concerned, the essential factors relating to the clinical background and the associated radiation risk are also outlined. The completeness of detail depends on the present clinical importance of the method under discussion. X-ray mammography, which is still the most important breast imaging technique and has proved to be an effective method for breast cancer screening, is therefore treated in greater detail. Since the early 1980s, ultrasound B-mode scanning has evolved to an indispensable adjunct to x-ray mammography. For Doppler sonography, diaphanography, contrast-enhanced MRI, CT and DSA, the visualization of a tumour depends essentially on the enhanced vascularity of the lesion. Whether this will prove to be a reliable indicator for malignancy remains to be shown in controlled clinical studies. Common to all imaging systems is the increasing use of digital methods for signal processing, which also offers the possibility of computer-aided diagnosis by texture analysis and pattern recognition.
1982年,本刊已发表过一篇关于乳腺成像的综述。因此,本文仅着重讨论那些较新的进展。尽管重点放在了相关不同成像方法的物理方面,但也概述了与临床背景及相关辐射风险有关的关键因素。细节的完整性取决于所讨论方法目前的临床重要性。因此,对X线乳腺摄影进行了更详细的论述,它仍是最重要的乳腺成像技术,已被证明是一种有效的乳腺癌筛查方法。自20世纪80年代初以来,超声B型扫描已发展成为X线乳腺摄影不可或缺的辅助手段。对于多普勒超声、透照法、对比增强磁共振成像、CT和DSA而言,肿瘤的可视化主要取决于病变血管的增强。这是否会被证明是恶性肿瘤的可靠指标,仍有待在对照临床研究中证实。所有成像系统的共同之处在于越来越多地使用数字方法进行信号处理,这也为通过纹理分析和模式识别进行计算机辅助诊断提供了可能。