Tomono N, Kuriyama T, Mori M, Takahashi Y, Mitsuda T, Aihara Y, Yokota S
Department of Pediatrics, Yokohama City University School of Medicine.
Ryumachi. 1996 Jun;36(3):522-7.
We reported a case with progressive systemic sclerosis, a relatively rare disease in childhood. Raynaud's phenomenon (RP) of the patient was serially monitored by computed thermography for 1 year. Although clinically apparent RP manifested only in winter season, thermographical changes were documented through all season, suggesting that RP is a constitutional sign which may emerge in winter by provocation of atmosphere. Thus, we recommend to use the words, "Raynaud's phenomenon" and " Raynaud's symptom", in an appropriate meaning. RP of the patient, however, varied depending on the time determined, which indicated that the cause of RP is not due to the irreversible tissue degenerations, but due to the reversible functional factors. Computed thermography was proved useful for detecting RP objectively, and will be valuable for estimating the effects of medications for RP.
我们报告了一例患有进行性系统性硬化症的病例，这是一种在儿童期相对罕见的疾病。通过计算机热成像对该患者的雷诺现象（RP）进行了为期1年的连续监测。尽管临床上明显的RP仅在冬季出现，但热成像变化在全年均有记录，这表明RP是一种体质性体征，可能在冬季因环境激发而出现。因此，我们建议以恰当的含义使用“雷诺现象”和“雷诺症状”这两个术语。然而，该患者的RP因所确定的时间不同而有所变化，这表明RP的病因并非不可逆的组织退化，而是可逆的功能因素。计算机热成像被证明可客观检测RP，并且对于评估治疗RP药物的效果将具有重要价值。
