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纵隔内注入表柔比星和5-氟尿嘧啶:完全植入式中心静脉系统的一种并发症。病例报告

Mediastinal infusion of epirubicin and 5-fluorouracil. A complication of totally implantable central venous systems. Report of a case.

作者信息

Rodier J M, Malbec L, Lauraine E P, Batel-Copel L, Bernadou A

机构信息

Department of Internal Medicine-Oncology, Hotel-Dieu, Paris, France.

出版信息

J Cancer Res Clin Oncol. 1996;122(9):566-7. doi: 10.1007/BF01213554.

DOI:10.1007/BF01213554
PMID:8781572
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12201224/
Abstract

Perforation of the wall of the superior vena cava by a central venous catheter is reported. The resultant inadvertent infusion of 5-fluorouracil and epirubicin caused a severe acute inflammatory reaction in the right-lobe bronchus, mediastinal infiltration and pleural and pericardial effusions. The patient recovered but has residual mild oesophageal dysfunction.

摘要

据报道,中心静脉导管导致上腔静脉壁穿孔。由此意外输注的5-氟尿嘧啶和表柔比星在右叶支气管引起了严重的急性炎症反应、纵隔浸润以及胸膜和心包积液。患者康复,但仍有轻度食管功能障碍残留。

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本文引用的文献

1
Intrapericardial infusion of 5-fluorouracil. An unusual complication of a Hickman catheter.心包内输注5-氟尿嘧啶。Hickman导管的一种罕见并发症。
Cancer. 1991 Feb 1;67(3):735-7. doi: 10.1002/1097-0142(19910201)67:3<735::aid-cncr2820670334>3.0.co;2-b.
2
Necrotizing pneumonitis caused by 5-fluorouracil infusion. A complication of a Hickman catheter.5-氟尿嘧啶输注引起的坏死性肺炎。希克曼导管的一种并发症。
Cancer. 1992 Jul 15;70(2):554-6. doi: 10.1002/1097-0142(19920715)70:2<554::aid-cncr2820700228>3.0.co;2-3.