Makarova I A, Bianki V L
Laboratory of the Neurobiology of Behavior, State University, Saint Petersburg.
Neurosci Behav Physiol. 1996 Mar-Apr;26(2):153-63. doi: 10.1007/BF02359419.
The characteristics of the dynamics of the functional interhemispheric asymmetry (FIAs) of the transcallosal influences in male and female rats were compared in this study through an analysis of the amplitude-temporal parameters of the homotopic transcallosal responses (TCR) in the course of their multiple topographical pickup from the dorsolateral surface of the cortex of both hemispheres in the time interval of the realization of the components of the responses. Two principal types of patterns of hemispheric dominance have been distinguished. The first type was described in accordance with the rule of the right-left-right shift of FIAs; the second type was described in accordance with the rule of its left-right-left shift. The changes in the FIAs of the temporal parameters of the positive components and the amplitude parameters of the positive and negative fluctuations were characterized by the identical type of dynamics in rats of both sexes. The dynamics of the FIAs of the temporal parameters of the negative components unfolded in accordance with the first type in the females, but in accordance with the second type in the males. The dominance of the investigated zones of the cortex of the right hemisphere was expressed more markedly in the females at the initial and terminal stages of the processing of transcallosal information. The phases of the dominance of the left hemisphere, by contrast, were identified and detected in a relatively larger territory of the neocortex examined in the males by comparison with the females. The results obtained suggest the relatively greater participation of the cortex of the right hemisphere in the females, but of the left hemisphere in the males during the processing of a transcallosal signal.
本研究通过分析在反应成分实现的时间间隔内，从双侧大脑半球皮质背外侧表面进行多次地形采集时，同位胼胝体反应（TCR）的振幅-时间参数，比较了雄性和雌性大鼠胼胝体间影响的功能半球间不对称（FIA）动力学特征。区分出两种主要的半球优势模式类型。第一种类型是根据FIA的右-左-右移位规则描述的；第二种类型是根据其左-右-左移位规则描述的。阳性成分的时间参数以及阳性和阴性波动的振幅参数的FIA变化在两性大鼠中具有相同类型的动力学特征。阴性成分的时间参数的FIA动力学在雌性中按照第一种类型展开，但在雄性中按照第二种类型展开。在胼胝体信息处理的初始和终末阶段，雌性右半球皮质的被研究区域优势表现得更为明显。相比之下，与雌性相比，在雄性检查的新皮质相对较大区域中识别和检测到了左半球优势阶段。获得的结果表明，在处理胼胝体信号期间，雌性右半球皮质的参与相对较多，而雄性左半球皮质的参与相对较多。
