Levey D L, Srivastava P K
Dept of Biological Sciences, Fordham University, Bronx, NY 10458, USA.
Immunol Today. 1996 Aug;17(8):365-8. doi: 10.1016/0167-5699(96)10013-X.
T cells of tumor-bearing mice and cancer patients have been reported to have altered signal-transduction machinery. These alterations have been implicated in immunological suppression. Here, Daniel Levey and Pramod Srivastava critically examine the evidence for these alterations in the context of the tumor specificity of immunological unresponsiveness in tumor-bearing hosts.
据报道，荷瘤小鼠和癌症患者的T细胞具有改变的信号转导机制。这些改变与免疫抑制有关。在此，丹尼尔·利维（Daniel Levey）和普拉莫德·斯里瓦斯塔瓦（Pramod Srivastava）在荷瘤宿主免疫无反应性的肿瘤特异性背景下，严格审查了这些改变的证据。
